2. Natural Products
  3. Disease Research Fields Plants Phenols Ketones, Aldehydes, Acids
  4. Rutaceae Other Diseases Monophenols
  5. Zanthoxylum bungeanum Maxim.
  6. Pluviatolide

Pluviatolide  (Synonyms: (-)-Pluviatolide)

Cat. No.: HY-N9926 Purity: ≥95.0%
SDS COA Handling Instructions

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Pluviatolide ((-)-Pluviatolide) is a lignan that can be found in the bark of Zanthoxylum pluviatile Hartley. Pluviatolide can be used as (-)-Podophyllotoxin precursor.

For research use only. We do not sell to patients.

Pluviatolide Chemical Structure

Pluviatolide Chemical Structure

CAS No. : 28115-68-6

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1 mg USD 600 In-stock
5 mg USD 1500 In-stock
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Based on 1 publication(s) in Google Scholar

Pluviatolide Related Antibodies

Top Publications Citing Use of Products

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Description

Pluviatolide ((-)-Pluviatolide) is a lignan that can be found in the bark of Zanthoxylum pluviatile Hartley. Pluviatolide can be used as (-)-Podophyllotoxin precursor[1][2].

Cellular Effect
Cell Line Type Value Description References
GLC4 cell line IC50
> 100 μM
Compound: 2
Cytotoxic effect against GLC4 (human small cell lung carcinoma cell line) using the microculture tetrazolium (MTT) assay based on 2 hr incubation
Cytotoxic effect against GLC4 (human small cell lung carcinoma cell line) using the microculture tetrazolium (MTT) assay based on 2 hr incubation
[PMID: 7783142]
GLC4 cell line IC50
6.5 μM
Compound: 2
Cytotoxic effect against GLC4 (human small cell lung carcinoma cell line) using the microculture tetrazolium (MTT) assay based on continuous incubation
Cytotoxic effect against GLC4 (human small cell lung carcinoma cell line) using the microculture tetrazolium (MTT) assay based on continuous incubation
[PMID: 7783142]
Molecular Weight

356.37

Formula

C20H20O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1OC[C@H](CC2=CC=C(OCO3)C3=C2)[C@H]1CC4=CC=C(O)C(OC)=C4
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 3.6 mg/mL (10.10 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8061 mL 14.0304 mL 28.0607 mL
5 mM 0.5612 mL 2.8061 mL 5.6121 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥95.0%

SDS (251 KB)

COA (260 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8061 mL 14.0304 mL 28.0607 mL 70.1518 mL
5 mM 0.5612 mL 2.8061 mL 5.6121 mL 14.0304 mL
10 mM 0.2806 mL 1.4030 mL 2.8061 mL 7.0152 mL
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Pluviatolide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pluviatolide28115-68-6(-)-PluviatolideOthersInhibitorinhibitorinhibit

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