2. Epigenetics
  3. Histone Acetyltransferase Epigenetic Reader Domain
  4. PNSC928

PNSC928 is an inhibitor for the CtBP2-p300 interaction with an IC50 of 23.60 µM, and reverses the Lipopolysaccharides (HY-D1056)-induced expressions of proinflammatory cytokines in RAW264.7. PNSC928 ameliorates the acute respiratory distress syndrome (ARDS)in mice.

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PNSC928 Chemical Structure

PNSC928 Chemical Structure

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PNSC928 Related Antibodies

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CBP/p300 GCN5/PCAF TIP60 MOZ/MORF HBO1

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Description

PNSC928 is an inhibitor for the CtBP2-p300 interaction with an IC50 of 23.60 µM, and reverses the Lipopolysaccharides (HY-D1056)-induced expressions of proinflammatory cytokines in RAW264.7. PNSC928 ameliorates the acute respiratory distress syndrome (ARDS)in mice[1].

Molecular Weight

402.57

Formula

C25H38O4
SMILES

O=C(C1)OC[C@]1([H])[C@@]2([H])CC=C(CC/C=C(C)/CCC3=C(C)CCCC3(C)C)[C@@](O)([H])O2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PNSC928 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PNSC928PNSC 928PNSC-928Histone AcetyltransferaseEpigenetic Reader DomainHATsHATRAW264.7acute respiratory distress syndromeARDSInhibitorinhibitorinhibit

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HY-159131
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