2. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. Transmembrane Glycoprotein ADC Antibody
  4. Polatuzumab

Polatuzumab is a monoclonal antibody that targets CD79b on the surface of B cells. Polatuzumab can be used to synthesize the ADC Polatuzumab Vedotin (HY-132253), which has anti-tumor activity.

For research use only. We do not sell to patients.

CAS No. : 2279068-37-8

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Based on 1 publication(s) in Google Scholar

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Polatuzumab Related Antibodies

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1 Publications Citing Use of MCE Polatuzumab

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Polatuzumab is a monoclonal antibody that targets CD79b on the surface of B cells. Polatuzumab can be used to synthesize the ADC Polatuzumab Vedotin (HY-132253), which has anti-tumor activity[1].

In Vitro

Polatuzumab Vedotin is composed of a humanized anti-CD79b monoclonal antibody linked to the synthetic microtubule-disrupting agent MMAE (HY-15162) via a cleavable peptide linker, and it can be used in the research of diffuse large B-cell lymphoma (DLBCL)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Polatuzumab Related Antibodies
Clinical Trial
Molecular Weight

145500.00

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Polatuzumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized CD79B Protein, Human (HY-P70541) can bind Polatuzumab, with the EC50 is 1.037 ng/mL.
Purity & Documentation

Purity: 99.69%

SDS (251 KB)

COA (231 KB) SDS-PAGE (88 KB) SEC-HPLC (223 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Polatuzumab Related Classifications

  • Molarity Calculator

  • Dilution Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polatuzumab2279068-37-8Transmembrane GlycoproteinADC Antibodymonoclonal antibodytargets CD79bADCDLBCLInhibitorinhibitorinhibit

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Polatuzumab
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HY-P99042
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