1. Immunology/Inflammation Metabolic Enzyme/Protease
  2. COX Carbonic Anhydrase
  3. Polmacoxib (Standard)

Polmacoxib (Standard) is the analytical standard of Polmacoxib. This product is intended for research and analytical applications. Polmacoxib (CG100649) is a first-in-class, orally active nonsteroidal anti-inflammatory agent (NSAID) which is a dual inhibitor of COX-2 (IC50 around 0.1 μg/ml) and carbonic anhydrase. Polmacoxib inhibits colorectal adenoma and tumor growth in mouse models.

For research use only. We do not sell to patients.

Polmacoxib (Standard) Chemical Structure

Polmacoxib (Standard) Chemical Structure

CAS No. : 301692-76-2

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Description
Molecular Weight

361.39

Formula

C18H16FNO4S

CAS No.
SMILES

O=S(C1=CC=C(C(OC2(C)C)=C(C3=CC=CC(F)=C3)C2=O)C=C1)(N)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Polmacoxib (Standard)
Cat. No.:
HY-16726R
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