Polygalacin D2

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Polygalacin D2 is a saponin isolated from Platycodon grandiflorum.

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Polygalacin D2 Chemical Structure

CAS No. : 66663-92-1

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Description

Polygalacin D2 is a saponin isolated from Platycodon grandiflorum^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-15	IC₅₀	3.8 μM Compound: 12	Antiproliferative activity against human HCT15 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 20939516]
HCT-15	IC₅₀	5.8 μM Compound: 12	Antiproliferative activity against human HCT15/CL02 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HCT15/CL02 cells after 48 hrs by sulforhodamine B assay	[PMID: 20939516]
MES-SA	IC₅₀	2.6 μM Compound: 12	Antiproliferative activity against human MESSA cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human MESSA cells after 48 hrs by sulforhodamine B assay	[PMID: 20939516]
MES-SA/Dx5	IC₅₀	3.4 μM Compound: 12	Antiproliferative activity against human MESSA/DX5 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human MESSA/DX5 cells after 48 hrs by sulforhodamine B assay	[PMID: 20939516]

Molecular Weight

1371.46

Formula

C₆₃H₁₀₂O₃₂

CAS No.

66663-92-1

SMILES

O[C@H]([C@@H]([C@H]([C@@H](O1)C)O[C@H]2[C@@H]([C@H]([C@@H](CO2)O)O[C@H]3[C@@H]([C@](O)(CO3)CO)O)O)O)[C@@H]1O[C@H]([C@H]([C@H](CO4)O)O)[C@@H]4OC([C@]56[C@](CC(C)(CC6)C)([H])C7=CC[C@@]([C@@]8([C@@]([C@](C)([C@H]([C@H](C8)O)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O[C@@H]%10O[C@@H]([C@H]([C@@H]([C@H]%10O)O)O)CO)O)CO)([H])CC%11)C)([H])[C@]%11(C)[C@@]7(C[C@H]5O)C)=O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kim YS, et al. Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines. Planta Med. 2005 Jun;71(6):566-8. [Content Brief]

Polygalacin D2 Related Classifications

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Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polygalacin D266663-92-1Polygalacin D 2Polygalacin D-2OthersSaponinInhibitorinhibitorinhibit

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