2. Immunology/Inflammation PI3K/Akt/mTOR NF-κB
  3. Toll-like Receptor (TLR) PI3K Akt NF-κB
  4. Polygalasaponin F (Standard)

Polygalasaponin F (Standard) 

Cat. No.: HY-N0392R Purity: ≥98%
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Polygalasaponin F (Standard) is the analytical standard of Polygalasaponin F. This product is intended for research and analytical applications. Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .

For research use only. We do not sell to patients.

Polygalasaponin F (Standard) Chemical Structure

Polygalasaponin F (Standard) Chemical Structure

CAS No. : 882664-74-6

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Description
Molecular Weight

1091.24

Formula

C53H86O23
CAS No.
SMILES

OC[C@H]1O[C@@]([H])(O[C@@H]2[C@@](C)(CO)[C@@](CC[C@]3(C)[C@]4([H])CC=C5[C@@]3(C)CC[C@]6(C(O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@]8([H])[C@H](O)[C@H](O)[C@@H](O[C@]9([H])OC[C@@H](O)[C@H](O)[C@H]9O)[C@H](C)O8)=O)[C@@]5([H])CC(C)(C)CC6)([H])[C@]4(C)C[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Structure Classification
Initial Source
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Polygalasaponin F (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polygalasaponin F (Standard)882664-74-6Toll-like Receptor (TLR)PI3KAktNF-κBPhosphoinositide 3-kinasePKBProtein kinase BNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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