2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Pomalidomide-5'-PEG8-C2-COOH

Pomalidomide-5'-PEG8-C2-COOH is an E3 Ligase Ligand-Linker Conjugates, consisting of Pomalidomide (HY-10984) and a linker. Pomalidomide-5'-PEG8-C2-COOH can be used for synthesis of PROTACs.

For research use only. We do not sell to patients.

Pomalidomide-5'-PEG8-C2-COOH Chemical Structure

Pomalidomide-5'-PEG8-C2-COOH Chemical Structure

CAS No. : 2138440-78-3

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5 mg USD 220 In-stock
10 mg USD 350 In-stock
25 mg USD 737 In-stock
50 mg USD 1180 In-stock
100 mg USD 1880 In-stock
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Based on 1 publication(s) in Google Scholar

Pomalidomide-5'-PEG8-C2-COOH Related Antibodies

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Description

Pomalidomide-5'-PEG8-C2-COOH is an E3 Ligase Ligand-Linker Conjugates, consisting of Pomalidomide (HY-10984) and a linker. Pomalidomide-5'-PEG8-C2-COOH can be used for synthesis of PROTACs[1].

Molecular Weight

697.73

Formula

C32H47N3O14
CAS No.
Appearance

Oil

Color

Light yellow to yellow

SMILES

O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (143.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4332 mL 7.1661 mL 14.3322 mL
5 mM 0.2866 mL 1.4332 mL 2.8664 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4332 mL 7.1661 mL 14.3322 mL 35.8305 mL
5 mM 0.2866 mL 1.4332 mL 2.8664 mL 7.1661 mL
10 mM 0.1433 mL 0.7166 mL 1.4332 mL 3.5830 mL
15 mM 0.0955 mL 0.4777 mL 0.9555 mL 2.3887 mL
20 mM 0.0717 mL 0.3583 mL 0.7166 mL 1.7915 mL
25 mM 0.0573 mL 0.2866 mL 0.5733 mL 1.4332 mL
30 mM 0.0478 mL 0.2389 mL 0.4777 mL 1.1943 mL
40 mM 0.0358 mL 0.1792 mL 0.3583 mL 0.8958 mL
50 mM 0.0287 mL 0.1433 mL 0.2866 mL 0.7166 mL
60 mM 0.0239 mL 0.1194 mL 0.2389 mL 0.5972 mL
80 mM 0.0179 mL 0.0896 mL 0.1792 mL 0.4479 mL
100 mM 0.0143 mL 0.0717 mL 0.1433 mL 0.3583 mL
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Pomalidomide-5'-PEG8-C2-COOH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide-5'-PEG8-C2-COOH2138440-78-3E3 Ligase Ligand-Linker ConjugatesE3 Ligase Ligand-LinkerPROTACsInhibitorinhibitorinhibit

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