2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Pomalidomide-PEG7-NH2 hydrochloride

Pomalidomide-PEG7-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG7-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC.

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Pomalidomide-PEG7-NH2 hydrochloride Chemical Structure

Pomalidomide-PEG7-NH2 hydrochloride Chemical Structure

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Pomalidomide-PEG7-NH2 hydrochloride Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor

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Description

Pomalidomide-PEG7-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG7-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].

Molecular Weight

618.07

Formula

C27H40ClN3O11
Appearance

Solid-Liquid Mixture

Color

Brown to reddish brown

SMILES

NCCOCCOCCOCCOCCOCCOCCOC1=CC=CC2=C1C(N(C3C(NC(CC3)=O)=O)C2=O)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
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Pomalidomide-PEG7-NH2 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide-PEG7-NH2E3 Ligase Ligand-Linker ConjugatesMolecular gelcereblon ligandPROTACCRBN proteintarget protein ligandconjugateInhibitorinhibitorinhibit

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Pomalidomide-PEG7-NH2 hydrochloride
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HY-155258
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