2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. PPARα/δ agonist 2

PPARα/γ agonist 4 (compound 14) is a potent PPARα and PPARδ agonist with EC50s of 3255 nM and 1475 nM for human PPARα and PPARβ/δ, respectively. PPARα/γ agonist 4 shows anti-inflammatory effects.

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PPARα/δ agonist 2 Chemical Structure

PPARα/δ agonist 2 Chemical Structure

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PPARα/δ agonist 2 Related Antibodies

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Description

PPARα/γ agonist 4 (compound 14) is a potent PPARα and PPARδ agonist with EC50s of 3255 nM and 1475 nM for human PPARα and PPARβ/δ, respectively. PPARα/γ agonist 4 shows anti-inflammatory effects[1].

IC50 & Target[1]

PPARα

3255 nM (EC50)

PPARβ/δ

1475 nM (EC50)

Molecular Weight

590.05

Formula

C31H32ClF4N3O2
SMILES

FC1=CC=C(COC2=CC(CCC(C)(CC/C=C(C)/CC/C=N/NC3=NC=C(Cl)C=C3C(F)(F)F)O4)=C4C=C2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PPARα/δ agonist 2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PPARα/δ agonist 2PPARPeroxisome proliferator-activated receptorsInhibitorinhibitorinhibit

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