Pregnanediol 3-glucuronide

Cat. No.: HY-W040047 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species.

For research use only. We do not sell to patients.

Pregnanediol 3-glucuronide Chemical Structure

CAS No. : 1852-49-9

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	Get quote
50 mg	Get quote

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Other Forms of Pregnanediol 3-glucuronide:

Pregnanediol 3-glucuronide-¹³C₅ Get quote

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Biological Activity
Purity & Documentation
References
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Description

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

496.63

Formula

C₂₇H₄₄O₈

CAS No.

1852-49-9

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([H])[C@](CC[C@]1([H])C[C@@H](CC2)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(O)=O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@@H](O)C)C

Structure Classification

Steroids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

Ethanol : 200 mg/mL (402.71 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0136 mL	10.0679 mL	20.1357 mL
5 mM	0.4027 mL	2.0136 mL	4.0271 mL
10 mM	0.2014 mL	1.0068 mL	2.0136 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (251 KB)

Handling Instructions (2659 KB)

References

[1]. Chen J, et al. Quantitation of serum pregnanediol-3-glucuronide level in different endocrine statuses by LC-MS/MS. J Pharm Biomed Anal. 2020;184:113171. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol	1 mM	2.0136 mL	10.0679 mL	20.1357 mL	50.3393 mL
	5 mM	0.4027 mL	2.0136 mL	4.0271 mL	10.0679 mL
	10 mM	0.2014 mL	1.0068 mL	2.0136 mL	5.0339 mL
	15 mM	0.1342 mL	0.6712 mL	1.3424 mL	3.3560 mL
	20 mM	0.1007 mL	0.5034 mL	1.0068 mL	2.5170 mL
	25 mM	0.0805 mL	0.4027 mL	0.8054 mL	2.0136 mL
	30 mM	0.0671 mL	0.3356 mL	0.6712 mL	1.6780 mL
	40 mM	0.0503 mL	0.2517 mL	0.5034 mL	1.2585 mL
	50 mM	0.0403 mL	0.2014 mL	0.4027 mL	1.0068 mL
	60 mM	0.0336 mL	0.1678 mL	0.3356 mL	0.8390 mL
	80 mM	0.0252 mL	0.1258 mL	0.2517 mL	0.6292 mL
	100 mM	0.0201 mL	0.1007 mL	0.2014 mL	0.5034 mL