2. PROTAC
  3. PROTAC Linkers
  4. Propargyl-PEG2-CH2COOH

Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Propargyl-PEG2-CH2COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

Propargyl-PEG2-CH2COOH Chemical Structure

Propargyl-PEG2-CH2COOH Chemical Structure

CAS No. : 944561-46-0

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Based on 1 publication(s) in Google Scholar

Propargyl-PEG2-CH2COOH Related Antibodies

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Description

Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-CH2COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target[1]

PEGs

 

Molecular Weight

202.20

Formula

C9H14O5
CAS No.
Appearance

Liquid (Density: 1.158±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(O)COCCOCCOCC#C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation

Purity: ≥95.0%

SDS (615 KB)

COA (241 KB) HNMR (95 KB)

Handling Instructions (2659 KB)
References
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Propargyl-PEG2-CH2COOH Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Propargyl-PEG2-CH2COOH944561-46-0PROTAC LinkersInhibitorinhibitorinhibit

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