Propionyl coenzyme A lithium

Cat. No.: HY-134424 Purity: 94%: FAQs
Data Sheet SDS COA Handling Instructions

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Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms.

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Propionyl coenzyme A lithium Chemical Structure

CAS No. : 108321-21-7

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1 mg	USD 320	In-stock	Estimated Time of Arrival: December 31
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Other Forms of Propionyl coenzyme A lithium:

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Description	Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms^[1]^[2].
In Vitro	Propionyl coenzyme A lithium causes toxic effects due to its accumulation and the impact of its metabolism on cell wall synthesis and maintenance in Mycobacterium tuberculosis^[1]. Propionyl coenzyme A lithium can be converted to β-hydroxypropionic acid via a peroxisomal enzyme-modified β-oxidation pathway in Arabidopsis^[2]. Propionyl coenzyme A lithium causes the formation of propionic acidemia due to its abnormal accumulation, which often occurs in the neonatal developmental stage^[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Propionyl coenzyme A lithium Related Antibodies
Formula	C₂₄H₄₀N₇O₁₇P₃S.xLi
CAS No.	108321-21-7
Appearance	Solid
Color	White to off-white
SMILES	CCC(SCCNC(CCNC([C@H](O)C(C)(C)COP(OP(OC[C@@H]1[C@@H](OP(O)(O)=O)[C@@H](O)[C@]([H])(N2C=NC3=C(N)N=CN=C32)O1)(O)=O)(O)=O)=O)=O)=O.[Li].[x]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility	In Vitro: H₂O : 50 mg/mL (Need ultrasonic and warming) Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight * Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details. The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE). Tel: 609-228-6898 E-mail: sales@medchemexpress.com Technical Support: tech@medchemexpress.com
Purity & Documentation	Purity: 94% Select Batch: Data Sheet (269 KB) SDS (393 KB) COA (245 KB) Handling Instructions (2659 KB)
References	[1]. Ernesto J Muñoz-Elías, et al. Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence. Mol Microbiol. 2006 Jun;60(5):1109-22. [Content Brief] [2]. Kerry A Lucas, et al. Peroxisomal metabolism of propionic acid and isobutyric acid in plants. J Biol Chem. 2007 Aug 24;282(34):24980-9. [Content Brief] [3]. Oleg A Shchelochkov, et al. Propionic Acidemia. 2012 May 17 [updated 2016 Oct 6]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2022. [Content Brief]