2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Propionyl-DL-carnitine chloride

Propionyl-DL-carnitine chloride 

Cat. No.: HY-101018 Purity: ≥98.0%
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Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation.

For research use only. We do not sell to patients.

Propionyl-DL-carnitine chloride Chemical Structure

Propionyl-DL-carnitine chloride Chemical Structure

CAS No. : 18828-58-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Propionyl-DL-carnitine chloride:

Propionyl-DL-carnitine chloride Related Antibodies

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Description

Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation[1][2][3][4].

In Vitro

Propionyl-DL-carnitine chloride shows protection to beta-thalassaemic erythrocytes from oxidative stress[1].
Propionyl-DL-carnitine chloride increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl camitine from pyruvate[2].
Propionyl-DL-carnitine chloride allows the endothelial cells to maintain their functionality and regulatory role on vessel activity for a longer time and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine formed by adenine nucleotide catabolism[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Propionyl-DL-carnitine chloride Related Antibodies
In Vivo

Propionyl-DL-carnitine chloride (2 mM/kg; p.o. once daily for 4 weeks) affects plasma and urine total carnitine concentrations of mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult age-matched male C57BL/6 mice[3]
Dosage: 2 mM/kg
Administration: Oral gavage; 2 mM/kg/day for 4 weeks
Result: Increased plasma and urine total carnitine concentrations, but showed no effect on the skeletal muscle carnitine content of mice.
Molecular Weight

253.72

Formula

C10H20ClNO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCC(OC(CC(O)=O)C[N+](C)(C)C)=O.[Cl-]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Methanol : 250 mg/mL (985.34 mM; Need ultrasonic)

DMSO : 100 mg/mL (394.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9414 mL 19.7068 mL 39.4135 mL
5 mM 0.7883 mL 3.9414 mL 7.8827 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / Methanol 1 mM 3.9414 mL 19.7068 mL 39.4135 mL 98.5338 mL
5 mM 0.7883 mL 3.9414 mL 7.8827 mL 19.7068 mL
10 mM 0.3941 mL 1.9707 mL 3.9414 mL 9.8534 mL
15 mM 0.2628 mL 1.3138 mL 2.6276 mL 6.5689 mL
20 mM 0.1971 mL 0.9853 mL 1.9707 mL 4.9267 mL
25 mM 0.1577 mL 0.7883 mL 1.5765 mL 3.9414 mL
30 mM 0.1314 mL 0.6569 mL 1.3138 mL 3.2845 mL
40 mM 0.0985 mL 0.4927 mL 0.9853 mL 2.4633 mL
50 mM 0.0788 mL 0.3941 mL 0.7883 mL 1.9707 mL
60 mM 0.0657 mL 0.3284 mL 0.6569 mL 1.6422 mL
80 mM 0.0493 mL 0.2463 mL 0.4927 mL 1.2317 mL
100 mM 0.0394 mL 0.1971 mL 0.3941 mL 0.9853 mL
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Propionyl-DL-carnitine chloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Propionyl-DL-carnitine18828-58-5Endogenous Metabolitecarnitineinflammationmiceoxygen reactiveoxidative stressInhibitorinhibitorinhibit

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