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  6. Prosaikogenin A

Prosaikogenin A is a triterpene saponin isolated from Clinopodium chinense. Prosaikogenin A has significant promoting effects on platelet aggregation with an EC50 value of 12.2 μM.

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Prosaikogenin A Chemical Structure

Prosaikogenin A Chemical Structure

CAS No. : 99365-21-6

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Based on 1 publication(s) in Google Scholar

Prosaikogenin A Related Antibodies

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Description

Prosaikogenin A is a triterpene saponin isolated from Clinopodium chinense. Prosaikogenin A has significant promoting effects on platelet aggregation with an EC50 value of 12.2 μM[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 50 μM
Compound: 18
Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
Bcap37 IC50
43.18 μM
Compound: 18
Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
HEK-293T CC50
24.52 μM
Compound: 8
Cytotoxicity against human 293T cells expressing Gluc assessed as inhibition of cell proliferation after 24 hrs by CCK8 assay
Cytotoxicity against human 293T cells expressing Gluc assessed as inhibition of cell proliferation after 24 hrs by CCK8 assay
[PMID: 28314599]
Hep 3B2 IC50
19.78 μM
Compound: 18
Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
HepG2 IC50
26.18 μM
Compound: 18
Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
MCF7 IC50
42.1 μM
Compound: 18
Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
Molecular Weight

618.84

Formula

C36H58O8
CAS No.
SMILES

C[C@]12[C@]3(C(C=C[C@]1([H])[C@@]4([C@@]([C@@](C)([C@H](CC4)O[C@H]5[C@@H]([C@H]([C@H]([C@H](O5)C)O)O)O)CO)([H])CC2)C)=C6[C@@]([C@H](C3)O)(CCC(C)(C6)C)CO)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Prosaikogenin A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prosaikogenin A99365-21-6OthersInhibitorinhibitorinhibit

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