Prostaglandin E2 Ethanolamide (Synonyms: PGE2 ethanolamide)

Cat. No.: HY-121996: FAQs
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Prostaglandin E2 Ethanolamide (PGE₂-EA), an analog of PGE2, can be formed enzymatically following COX-2 oxygenation of endocannabinoids. Prostaglandin E2 Ethanolamide (PGE₂-EA) could modulate the production of the proinflammatory cytokine TNF-α in human blood and human monocytic cells.

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Prostaglandin E2 Ethanolamide Chemical Structure

CAS No. : 194935-38-1

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Other Forms of Prostaglandin E2 Ethanolamide:

Prostaglandin E2 Ethanolamide-d4 Get quote

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Description	Prostaglandin E2 Ethanolamide (PGE₂-EA), an analog of PGE2, can be formed enzymatically following COX-2 oxygenation of endocannabinoids. Prostaglandin E2 Ethanolamide (PGE₂-EA) could modulate the production of the proinflammatory cytokine TNF-α in human blood and human monocytic cells^[1]^[2].
Molecular Weight	395.53
Formula	C₂₂H₃₇NO₅
CAS No.	194935-38-1
SMILES	CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)C/C=C\CCCC(NCCO)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Kevin R Kozak, et al. Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. J Biol Chem. 2002 Nov 22;277(47):44877-85. [Content Brief] [2]. Kirsten L Brown, et al. Characterisation of the prostaglandin E2-ethanolamide suppression of tumour necrosis factor-α production in human monocytic cells. Biochim Biophys Acta. 2013 Jun;1831(6):1098-107. [Content Brief]

Prostaglandin E2 Ethanolamide Related Classifications

Inflammation/Immunology

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prostaglandin E2 Ethanolamide194935-38-1PGE2 ethanolamideProstaglandin ReceptorCOXCyclooxygenasePGE2COX-2,Inhibitorinhibitorinhibit

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