2. PROTAC PI3K/Akt/mTOR Cell Cycle/DNA Damage
  3. PROTACs ATM/ATR
  4. PROTAC ATR degrader-1

PROTAC ATR degrader-1 (compound ZS-7) is a potent PROTAC degrader of ataxia telangiectasia and Rad3-related (ATR), with DC50 of 0.53 μM. PROTAC ATR degrader-1 plays an importnt role in cancer research.

For research use only. We do not sell to patients.

PROTAC ATR degrader-1 Chemical Structure

PROTAC ATR degrader-1 Chemical Structure

CAS No. : 2925916-30-7

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PROTAC ATR degrader-1 Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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ATM ATR

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Description

PROTAC ATR degrader-1 (compound ZS-7) is a potent PROTAC degrader of ataxia telangiectasia and Rad3-related (ATR), with DC50 of 0.53 μM. PROTAC ATR degrader-1 plays an importnt role in cancer research[1].

Molecular Weight

933.05

Formula

C46H52N12O8S
CAS No.
SMILES

O=C(N1C2C(NC(CC2)=O)=O)C3=C(C=CC=C3C1=O)NC(CCCCCCCN4N=NC(CCC(N=[S@](C5(C6=CC(N7[C@@H](COCC7)C)=NC(C8=CC=NC9=C8C=CN9)=N6)CC5)(C)=O)=O)=C4)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC ATR degrader-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC ATR degrader-12925916-30-7PROTAC ATR degrader1PROTAC ATR degrader 1PROTACsATM/ATRAtaxia telangiectasia mutatedATM and RAD3 relatedHCT116 (ATMWT) cellsAZD6738ubiquitin-proteasome systemInhibitorinhibitorinhibit

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