2. PROTAC Immunology/Inflammation
  3. PROTACs IRAK
  4. PROTAC IRAK4 degrader-4

PROTAC IRAK4 degrader-4 is a Cereblon-based PROTAC as interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-127.

For research use only. We do not sell to patients.

PROTAC IRAK4 degrader-4 Chemical Structure

PROTAC IRAK4 degrader-4 Chemical Structure

CAS No. : 2360528-45-4

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PROTAC IRAK4 degrader-4 Related Antibodies

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IRAK1 IRAK4

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Description

PROTAC IRAK4 degrader-4 is a Cereblon-based PROTAC as interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-127[1].

IC50 & Target[1]

IRAK4

 

In Vitro

PROTAC IRAK4 degrader-4 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PROTAC IRAK4 degrader-4 Related Antibodies
Molecular Weight

901.80

Formula

C41H38F3N11O10
CAS No.
SMILES

O=C(C1=NN(C2=CC=C(C(NCCOCCOCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)C=C2)C=C1NC(C6=COC(C7=CC(NCC(F)(F)F)=NC=C7)=N6)=O)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC IRAK4 degrader-4 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC IRAK4 degrader-42360528-45-4PROTACsIRAKInterleukin-1 receptor associated kinaseIL-1R associated kinaseinterleukin-1receptor-associatedkinaseInhibitorinhibitorinhibit

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PROTAC IRAK4 degrader-4
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