2. PROTAC Apoptosis Metabolic Enzyme/Protease
  3. PROTACs MDM-2/p53 E1/E2/E3 Enzyme
  4. PROTAC MDM2 Degrader-4

PROTAC MDM2 Degrader-4 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-4 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase.

For research use only. We do not sell to patients.

PROTAC MDM2 Degrader-4 Chemical Structure

PROTAC MDM2 Degrader-4 Chemical Structure

CAS No. : 2249750-24-9

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PROTAC MDM2 Degrader-4 Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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Description

PROTAC MDM2 Degrader-4 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-4 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1].

IC50 & Target

MDM2

 

Molecular Weight

1393.19

Formula

C70H74Cl4N8O14
CAS No.
SMILES

O=C(N1CC(N(CC(OCCOCCOCCOC(CN2C(CN(C(N3[C@H](C4=CC=C(Cl)C=C4)[C@H](C5=CC=C(Cl)C=C5)N=C3C6=C(C=C(OC)C=C6)OC(C)C)=O)CC2)=O)=O)=O)CC1)=O)N7[C@H](C8=CC=C(Cl)C=C8)[C@H](C9=CC=C(Cl)C=C9)N=C7C%10=C(C=C(OC)C=C%10)OC(C)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC MDM2 Degrader-4 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC MDM2 Degrader-42249750-24-9PROTACsMDM-2/p53E1/E2/E3 EnzymeE1 activating enzymeE2 conjugating enzymeE3 ligating enzymeUbiquitin activating enzymeUbiquitin conjugating enzymeUbiquitin ligaseInhibitorinhibitorinhibit

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