2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc

PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc 

Cat. No.: HY-163217
Handling Instructions

Molarity Calculator

PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.

For research use only. We do not sell to patients.

PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc Chemical Structure

PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc Chemical Structure

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PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc Related Antibodies

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View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor

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Description

PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc can be used as a key intermediate for the synthesis of complete PROTAC molecules.

IC50 & Target

von Hippel-Lindau (VHL)[1]
Molecular Weight

692.87

Formula

C36H48N6O6S
SMILES

O=C([C@H]1N(C[C@@H](C1)O)C(C(C(C)C)C2=CC(N3CC4(CCN(CC4)C(OC(C)(C)C)=O)C3)=NO2)=O)NCC(C=C5)=CC=C5C(SC=N6)=C6C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-BocE3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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PROTAC PTK6 ligand-2,7-diazaspiro[3.5]nonane-Boc
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