2. PROTAC Anti-infection
  3. PROTACs SARS-CoV
  4. PROTAC SARS-CoV-2 Mpro degrader-1

PROTAC SARS-CoV-2 Mpro degrader-1 (compound 5) is a PROTAC degrader targeting the major SARS-CoV-2 protease with broad-spectrum antiviral activity.

For research use only. We do not sell to patients.

PROTAC SARS-CoV-2 Mpro degrader-1 Chemical Structure

PROTAC SARS-CoV-2 Mpro degrader-1 Chemical Structure

CAS No. : 3029579-46-9

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PROTAC SARS-CoV-2 Mpro degrader-1 Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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Description

PROTAC SARS-CoV-2 Mpro degrader-1 (compound 5) is a PROTAC degrader targeting the major SARS-CoV-2 protease with broad-spectrum antiviral activity[1].

IC50 & Target

SARS-CoV[1]
Molecular Weight

995.62

Formula

C52H63ClN8O8S
CAS No.
SMILES

ClC1=CC=C(C(N2C3=CC=C(OC)C=C3C(CC(NCCN4CCN(CC4)C(CCC(N[C@H](C(N5[C@@H](C[C@H](C5)O)C(N[C@@H](C)C6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)C(C)(C)C)=O)=O)=O)=C2C)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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PROTAC SARS-CoV-2 Mpro degrader-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC SARS-CoV-2 Mpro degrader-13029579-46-9PROTACsSARS-CoVSARS coronavirusSARS-CoV-2proteaseInhibitorinhibitorinhibit

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