2. Epigenetics
  3. Epigenetic Reader Domain
  4. PROTAC SMARCA2/4 degrader-37

PROTAC SMARCA2/4 degrader-37 (Example 4) is a PROTAC-based SMARCA2/4 degrader, with an IC50 of ≤0.1 μM (Pink: SMARCA2/4 lignad (HY-172446); Black: CRBN ligand (HY-41547); Linker (HY-N2407)).

For research use only. We do not sell to patients.

PROTAC SMARCA2/4 degrader-37 Chemical Structure

PROTAC SMARCA2/4 degrader-37 Chemical Structure

CAS No. : 2688882-69-9

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PROTAC SMARCA2/4 degrader-37 Related Antibodies

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Description

PROTAC SMARCA2/4 degrader-37 (Example 4) is a PROTAC-based SMARCA2/4 degrader, with an IC50 of ≤0.1 μM (Pink: SMARCA2/4 lignad (HY-172446); Black: CRBN ligand (HY-41547); Linker (HY-N2407))[1].

Molecular Weight

719.15

Formula

C37H31ClN8O6
CAS No.
SMILES

O=C(NC1=CC(C#CC2=CC=CC(C(NCCCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)=C2)=NC=C1)NC6=CC(Cl)=NC=C6
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC SMARCA2/4 degrader-37 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC SMARCA2/4 degrader-372688882-69-9Epigenetic Reader DomainInhibitorinhibitorinhibit

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