2. Anti-infection
  3. Bacterial
  4. Protein kinase G inhibitor-1

Protein kinase G inhibitor-1 (Compound 270) is a mycobacterial protein kinase G inhibitor, with an IC50 of 0.9 μM. Protein kinase G inhibitor-1 can be used for mycobacterial infection research.

For research use only. We do not sell to patients.

Protein kinase G inhibitor-1 Chemical Structure

Protein kinase G inhibitor-1 Chemical Structure

CAS No. : 354544-70-0

Size Price Stock Quantity
1 mg USD 190 In-stock
5 mg USD 440 In-stock
10 mg USD 650 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Protein kinase G inhibitor-1 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Protein kinase G inhibitor-1 (Compound 270) is a mycobacterial protein kinase G inhibitor, with an IC50 of 0.9 μM. Protein kinase G inhibitor-1 can be used for mycobacterial infection research[1].

IC50 & Target

0.9 μM (mycobacterial protein kinase G)[1]
Molecular Weight

278.37

Formula

C14H18N2O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C(NC(C2CC2)=O)SC3=C1CCC(C3)C)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (359.23 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5923 mL 17.9617 mL 35.9234 mL
5 mM 0.7185 mL 3.5923 mL 7.1847 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5923 mL 17.9617 mL 35.9234 mL 89.8085 mL
5 mM 0.7185 mL 3.5923 mL 7.1847 mL 17.9617 mL
10 mM 0.3592 mL 1.7962 mL 3.5923 mL 8.9809 mL
15 mM 0.2395 mL 1.1974 mL 2.3949 mL 5.9872 mL
20 mM 0.1796 mL 0.8981 mL 1.7962 mL 4.4904 mL
25 mM 0.1437 mL 0.7185 mL 1.4369 mL 3.5923 mL
30 mM 0.1197 mL 0.5987 mL 1.1974 mL 2.9936 mL
40 mM 0.0898 mL 0.4490 mL 0.8981 mL 2.2452 mL
50 mM 0.0718 mL 0.3592 mL 0.7185 mL 1.7962 mL
60 mM 0.0599 mL 0.2994 mL 0.5987 mL 1.4968 mL
80 mM 0.0449 mL 0.2245 mL 0.4490 mL 1.1226 mL
100 mM 0.0359 mL 0.1796 mL 0.3592 mL 0.8981 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Protein kinase G inhibitor-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Protein kinase G inhibitor-1354544-70-0Protein kinase G inhibitor1Protein kinase G inhibitor 1BacterialMycobacterialinfectionPKGInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Protein kinase G inhibitor-1
Cat. No.:
HY-48958
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.