2. Protein Tyrosine Kinase/RTK
  3. DYRK
  4. Protein kinase inhibitor 1

Protein kinase inhibitor 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Protein kinase inhibitor 1 hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Protein kinase inhibitor 1 Chemical Structure

Protein kinase inhibitor 1 Chemical Structure

CAS No. : 1365986-44-2

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Protein kinase inhibitor 1 Related Antibodies

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Description

Protein kinase inhibitor 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.

IC50 & Target

IC50: 74 nM (HIPK2)[1]
Kd: 9.5 nM (HIPK2)[1]
Molecular Weight

383.42

Formula

C18H17N5O3S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(NC/1=O)SC1=C\C2=CNC(C(C3=CC=C(N4CCNCC4)N=C3)=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

COA (247 KB)

Handling Instructions (2659 KB)
References
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Protein kinase inhibitor 1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Protein kinase inhibitor 11365986-44-2Protein kinase inhibitor1Protein kinase inhibitor-1DYRKDual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinaseInhibitorinhibitorinhibit

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Protein kinase inhibitor 1
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HY-U00439
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