2. Protein Tyrosine Kinase/RTK Neuronal Signaling
  3. Trk Receptor ROS Kinase
  4. Protein kinase inhibitor 4

Protein kinase inhibitor 4 (Compound 3) is a protein kinase inhibitor that inhibits TRK-A and ROS1 (IC50=3.0 nM and 104 nM respectively).

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Protein kinase inhibitor 4 Chemical Structure

Protein kinase inhibitor 4 Chemical Structure

CAS No. : 2278205-04-0

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Protein kinase inhibitor 4 Related Antibodies

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Description

Protein kinase inhibitor 4 (Compound 3) is a protein kinase inhibitor that inhibits TRK-A and ROS1 (IC50=3.0 nM and 104 nM respectively)[1].

IC50 & Target

IC50: 3.0 nM (Trk-A), 104 nM (ROS-1)[1]
Molecular Weight

526.56

Formula

C25H24F2N6O3S
CAS No.
SMILES

FC1=C(C=C(C=C1)F)[C@@H]2N(C3=NC4=C(C=NN4C=C3)NC(C5=CC=C(C=C5)NS(CC)(=O)=O)=O)CCC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Protein kinase inhibitor 4 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Protein kinase inhibitor 42278205-04-0Protein kinase inhibitor4Protein kinase inhibitor-4Trk ReceptorROS KinaseTropomyosin related kinase receptorProtein kinaseTRK-AROS1Inhibitorinhibitorinhibit

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Protein kinase inhibitor 4
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HY-153743
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