2. Recombinant Proteins
  3. Enzymes & Regulators
  4. ADAMs/ADAMTSs
  5. ADAM17/TACE

ADAM17/TACE

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72815
    ADAM17/TACE Protein, Rat (HEK293, His)

    Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; TNF-alpha convertase; CD156b; Tace

    		Rat HEK293
    ADAM17/TACE Protein, a pivotal enzyme, cleaves TNF-alpha and activates various cell-surface proteins like p75 TNF-receptor. It also mediates the cleavage of Notch, activates the Notch pathway, and contributes to hemostasis by shedding GP1BA. ADAM17/TACE further facilitates the cleavage of LAG3, IL6R, and FCGR3A, showcasing its significance in diverse cellular functions. ADAM17/TACE Protein, Rat (HEK293, His) is the recombinant rat-derived ADAM17/TACE protein, expressed by HEK293 , with C-10*His labeled tag. The total length of ADAM17/TACE Protein, Rat (HEK293, His) is 546 a.a., with molecular weight of 57 & 20 kDa, respectively.
  • HY-P78717
    ADAM17/TACE Protein, Mouse (HEK293, His)

    ADAM17; TACE; CD156b

    		Mouse HEK293
    The ADAM17/TACE protein cleaves TNF-α, releasing it from the membrane and activating various cell surface proteins such as JAM3, ACE2, and the p75 TNF receptor. It also triggers the Notch pathway by cleaving Notch into membrane-associated fragments. ADAM17/TACE Protein, Mouse (HEK293, His) is the recombinant mouse-derived ADAM17/TACE protein, expressed by HEK293 , with C-His labeled tag. The total length of ADAM17/TACE Protein, Mouse (HEK293, His) is 546 a.a..
Cat. No. Product Name Effect Purity