2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-1R
  6. IL-1 Receptor Accessory Proteins

IL-1 Receptor Accessory Proteins

Recombinant Protein Expression Service

IL-1 Receptor Accessory Proteins

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Interleukin-1 receptor accessory protein (IL-1RAcP) (EC:3.2.2.6), also known as IL-1 R3, belongs to the immunoglobulin (Ig) superfamily. It contains three Ig-like domains and a cytoplasmic domain named Toll/IL-1 receptor (TIR), which has been implicated in signal transduction. IL-1RAcP also contains a single transmembrane region. IL-1RAcP can be detected in liver, skin, placenta, thymus and lung. There are four isoforms of IL-1RAcP, the membranous form plays an important role in IL-1, IL-33, IL-36 signing, as well as FLT3 and C-Kit in AML cells. The isoform 2 and 3 are soluble forms, contribute to the regulation of the inflammation induced by IL-1. The isoform 4 is mainly expressed in CNS neurons. IL-1RAcP is an essential component of the IL-1 receptor and can be used for the research of inflammatory disorders. The sequence of amino acids in IL-1RAcP proteins from different species is relatively stable (over 85% identity between human, mouse and rat)[1][2].

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72565
    IL-1RAcP/IL-1 R3 Protein, Human (HEK293, His)

    Interleukin-1 Receptor Accessory Protein; IL-1RAcP; Interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		Human HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Human (HEK293, His) is a recombinant human IL-1RAcP protein with a His tag at the C-terminus and is expressed in HEK293 cells.
  • HY-P77413
    IL-1RAcP/IL-1 R3 Protein, Human (HEK293, Fc)

    Interleukin-1 Receptor Accessory Protein; IL-1RAcP; Interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		Human HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Human (HEK293, Fc) is a recombinant human IL-1RAcP protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 359 amino acids (M1-E359).
  • HY-P77412
    IL-1RAcP/IL-1 R3 Protein, Cynomolgus (HEK293, His)

    Interleukin-1 Receptor Accessory Protein; IL-1RAcP; Interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		Cynomolgus HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus IL-1RAcP protein with a His tag at the C-terminus and is expressed in HEK293 cells.
  • HY-P77417
    IL-1RAcP/IL-1 R3 Protein, Mouse (HEK293, Fc)

    Interleukin-1 Receptor Accessory Protein; IL-1RAcP; Interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		Mouse HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Mouse (HEK293, Fc) is a recombinant mouse IL-1RAcP protein with an hFc tag at the C-terminus and is expressed in HEK293 cells.
  • HY-P78463
    IL-1RAcP/IL-1 R3 Protein, Human (HEK293, His-Avi)

    IL1RAP; C3orf13; IL-1 R3; IL-1 RAcP

    		Human HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Human (HEK293, His-Avi) is a recombinant human IL-1RAcP protein with a His and an Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 339 amino acids (S21-E359).
  • HY-P701305
    FITC-Labeled IL-1RAcP/IL-1 R3 Protein, Human (HEK293, His)

    IL1RAP; IL-1RAcP; C3orf13; IL1R3

    		Human HEK293
    IL-1RAcP/IL-1 R3 protein is a co-receptor in the IL-36 and IL-1 signaling systems, forming a receptor complex to activate NF-kappa-B and other pathways. FITC-Labeled IL-1RAcP/IL-1 R3 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled IL-1RAcP/IL-1 R3 protein, expressed by HEK293 , with His labeled tag.
  • HY-P78146
    IL-1RAcP/IL-1 R3 Protein, Human (Biotinylated, HEK293, His-Avi)

    IL1RAP; C3orf13; IL-1 R3; IL-1 RAcP

    		Human HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Human (339a.a, Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IL-1RAcP protein with an Avi tag and a His tag at the C-terminus and is expressed in HEK293 cells. It consists of 339 amino acids (S21-E359).
  • HY-P77411
    IL-1RAcP/IL-1 R3 Protein, Cynomolgus (HEK293, Fc)

    Interleukin-1 Receptor Accessory Protein; IL-1RAcP; Interleukin-1 Receptor 3; IL-1R3; IL1RAP; C3orf13

    		Cynomolgus HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Cynomolgus (HEK293, Fc) is a recombinant cynomolgus IL-1RAcP protein with an hFc tag at the C-terminus and is expressed in HEK293 cells.
  • HY-P78311
    IL-1RAcP/IL-1 R3 Protein, Mouse (HEK293, His)

    IL1RAP; C3orf13; IL-1 R3; IL-1 RAcP

    		Mouse HEK293
    IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process. IL-1RAcP/IL-1 R3 Protein, Mouse (HEK293, His) is a recombinant mouse IL-1RAcP protein with a His tag at the C-terminus and is expressed in HEK293 cells.
Cat. No. Product Name Effect Purity