2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. PSDalpha

PSDalpha is an ERα degrader conjugating photosensitizer (PS), triphenylamine benzothiadiazole (TB) and 17β-estradiol via an acetylene bond. PSDalpha shows excellent anti-proliferation performance on MCF-7 cells. The maximum absorption wavelength of PSDalpha in the visible region is located at 465 nm.

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PSDalpha Chemical Structure

PSDalpha Chemical Structure

CAS No. : 2906869-08-5

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PSDalpha Related Antibodies

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Description

PSDalpha is an ERα degrader conjugating photosensitizer (PS), triphenylamine benzothiadiazole (TB) and 17β-estradiol via an acetylene bond. PSDalpha shows excellent anti-proliferation performance on MCF-7 cells. The maximum absorption wavelength of PSDalpha in the visible region is located at 465 nm[1].

IC50 & Target[1]

ERα

 

Molecular Weight

673.86

Formula

C44H39N3O2S
CAS No.
SMILES

C[C@@]12[C@](CC[C@]2(O)C#CC3=CC=C(C4=CC=C(C=C4)N(C5=CC=CC=C5)C6=CC=CC=C6)C7=NSN=C37)([H])[C@@]8([H])[C@@](CC1)([H])C9=CC=C(O)C=C9CC8
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Purity & Documentation
References
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PSDalpha Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PSDalpha2906869-08-5Estrogen Receptor/ERRERα degraderphotosensitizer17β-estradiolanti-proliferationInhibitorinhibitorinhibit

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