2. Natural Products
  3. Plants Flavonoids
  4. Leguminosae Flavones
  5. Pterocarpus marsupium Roxb.
  6. Pseudobaptigenin

Pseudobaptigenin is a flavonoid. Pseudobaptigenin shows very good anticataract activity. Pseudobaptigenin has good binding affinity for the inhibition of glycation against γ-crystallin protein. Pseudobaptigenin also has good ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) property.

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Pseudobaptigenin Chemical Structure

Pseudobaptigenin Chemical Structure

CAS No. : 90-29-9

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Pseudobaptigenin Related Antibodies

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Description

Pseudobaptigenin is a flavonoid. Pseudobaptigenin shows very good anticataract activity. Pseudobaptigenin has good binding affinity for the inhibition of glycation against γ-crystallin protein. Pseudobaptigenin also has good ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) property[1].

Cellular Effect
Cell Line Type Value Description References
BV-2 IC50
> 100 μM
Compound: 20
Anti-neuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Anti-neuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
[PMID: 25466192]
C2C12 IC50
12.08 μg/mL
Compound: 7
Cytotoxicity against mouse C2C12 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse C2C12 cells assessed as reduction in cell viability by MTT assay
[PMID: 33412152]
HEK293 EC50
22.34 μM
Compound: 7
Agonist activity at human PPARdelta expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
Agonist activity at human PPARdelta expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
[PMID: 23265844]
HEK293 EC50
26.94 μM
Compound: 7
Agonist activity at human PPARgamma expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
Agonist activity at human PPARgamma expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
[PMID: 23265844]
HEK293 EC50
8.9 μM
Compound: 7
Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
[PMID: 23265844]
MCF7 IC50
> 100 μM
Compound: 30a
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS/PMS assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS/PMS assay
[PMID: 19932969]
SK-BR-3 IC50
> 100 μM
Compound: 30a
Antiproliferative activity against human SKBR3 cells after 72 hrs by MTS/PMS assay
Antiproliferative activity against human SKBR3 cells after 72 hrs by MTS/PMS assay
[PMID: 19932969]
Molecular Weight

282.25

Formula

C16H10O5
CAS No.
SMILES

O=C1C2=CC=C(C=C2OC=C1C3=CC4=C(OCO4)C=C3)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pseudobaptigenin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pseudobaptigenin90-29-9Othersanticataract activityflavonoidglycationγ-crystallin proteinInhibitorinhibitorinhibit

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