2. Anti-infection
  3. HCV
  4. PSI-6206-13C,d3

PSI-6206-13C,d3  (Synonyms: RO-2433-13C,d3; GS-331007-13C,d3; Sofosbuvir metabolite GS-331007-13C,d3)

Cat. No.: HY-15236S Purity: ≥99.0%
COA Handling Instructions

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PSI-6206-13C,d3 is the deuterium labeled PSI-6206. PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibits HCV replicon with EC90 of >100 μM.

For research use only. We do not sell to patients.

PSI-6206-<sup>13</sup>C,d<sub>3</sub> Chemical Structure

PSI-6206-13C,d3 Chemical Structure

CAS No. : 1256490-42-2

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1 mg USD 340 In-stock
5 mg USD 1350 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of PSI-6206-13C,d3:

PSI-6206-13C,d3 Related Antibodies

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Description

PSI-6206-13C,d3 is the deuterium labeled PSI-6206. PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibits HCV replicon with EC90 of >100 μM.

Molecular Weight

264.23

Formula

C913CH10D3FN2O5
CAS No.
Unlabeled CAS

863329-66-2
Appearance

Solid

Color

White to light yellow

SMILES

OC[C@@H]1[C@H]([C@@]([13C]([2H])([2H])[2H])(F)[C@H](N2C(NC(C=C2)=O)=O)O1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (378.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 100 mg/mL (378.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7846 mL 18.9229 mL 37.8458 mL
5 mM 0.7569 mL 3.7846 mL 7.5692 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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=
Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (255 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 3.7846 mL 18.9229 mL 37.8458 mL 94.6145 mL
5 mM 0.7569 mL 3.7846 mL 7.5692 mL 18.9229 mL
10 mM 0.3785 mL 1.8923 mL 3.7846 mL 9.4615 mL
15 mM 0.2523 mL 1.2615 mL 2.5231 mL 6.3076 mL
20 mM 0.1892 mL 0.9461 mL 1.8923 mL 4.7307 mL
25 mM 0.1514 mL 0.7569 mL 1.5138 mL 3.7846 mL
30 mM 0.1262 mL 0.6308 mL 1.2615 mL 3.1538 mL
40 mM 0.0946 mL 0.4731 mL 0.9461 mL 2.3654 mL
50 mM 0.0757 mL 0.3785 mL 0.7569 mL 1.8923 mL
60 mM 0.0631 mL 0.3154 mL 0.6308 mL 1.5769 mL
80 mM 0.0473 mL 0.2365 mL 0.4731 mL 1.1827 mL
100 mM 0.0378 mL 0.1892 mL 0.3785 mL 0.9461 mL
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PSI-6206-13C,d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PSI-6206-13C,d31256490-42-2RO-2433-13C,d3GS-331007-13C,d3Sofosbuvir metabolite GS-331007-13C,d3HCVHepatitis C virusInhibitorinhibitorinhibit

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