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  4. Purine phosphoribosyltransferase-IN-2

Purine phosphoribosyltransferase-IN-2 is a potent inhibitor of the Plasmodium falciparum ((Pf)), Plasmodium vivax ((Pv)) and Trypanosoma brucei ((Tbr)) 6-oxopurine phosphoribosyltransferase (PRT), with Kis of 30, 20 and 2 nM, respectively.

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Purine phosphoribosyltransferase-IN-2 Chemical Structure

Purine phosphoribosyltransferase-IN-2 Chemical Structure

CAS No. : 2784631-30-5

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Purine phosphoribosyltransferase-IN-2 Related Antibodies

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Description

Purine phosphoribosyltransferase-IN-2 is a potent inhibitor of the Plasmodium falciparum ((Pf)), Plasmodium vivax ((Pv)) and Trypanosoma brucei ((Tbr)) 6-oxopurine phosphoribosyltransferase (PRT), with Kis of 30, 20 and 2 nM, respectively[1].

IC50 & Target

Plasmodium

 

Trypanosoma

 

Molecular Weight

531.17

Formula

C11H15N5Na4O10P2
CAS No.
SMILES

O=P(O[Na])(O[Na])COC[C@@H](OC[C@H](P(O[Na])(O[Na])=O)O)CN1C=NC2=C1N=C(N)NC2=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Purine phosphoribosyltransferase-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Purine phosphoribosyltransferase-IN-22784631-30-5Parasiteparasite6-oxopurine phosphoribosyltransferasesP. falciparumP. vivaxanti-malarialT. bruceiInhibitorinhibitorinhibit

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