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  4. Purpurin 18 methyl ester

Purpurin 18 methyl ester, a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). Purpurin 18 methyl ester has photodynamic activity to induce cancer cell death.

For research use only. We do not sell to patients.

Purpurin 18 methyl ester Chemical Structure

Purpurin 18 methyl ester Chemical Structure

CAS No. : 51744-55-9

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Description

Purpurin 18 methyl ester, a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). Purpurin 18 methyl ester has photodynamic activity to induce cancer cell death[1].

In Vitro

Purpurin 18 methyl ester (1-5 μg/mL; 24 h) has no cytotoxicity in dark in HepG-2 cells[1].
Purpurin 18 methyl ester (1-5 μg/mL; 24 h) decreases the viability of HepG-2 cells in a concentration-dependent manner with irradiation for 10 min[1].
Purpurin 18 methyl ester (0-24 h) is released from GO- Purpurin 18 methyl ester (Pu18) composite, with rates of 47%, 22% and 30% in weak acidic condition (pH 5.6), neutral environment (pH 7.4) and weak alkali condition (pH 8.9) for 24 h, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

578.66

Formula

C34H34N4O5

CAS No.
SMILES

O=C(OC1=O)/C(C2=C1C(C)=C(/C=C3C(CC)=C4C)N2)=C(N=C(/C=C(C(C)=C/5C=C)\NC5=C/C4=N/3)[C@H]6C)\[C@H]6CCC(OC)=O

Structure Classification
Initial Source

sponge Stelletta clavosa

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Purpurin 18 methyl ester
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HY-137474
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