Pyrithiamine hydrobromide

Name: Pyrithiamine hydrobromide
Brand: MedChemExpress
SKU: HY-122273
Rating: 4.5 (1 reviews)

Cat. No.: HY-122273 Purity: 96.61%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Pyrithiamine hydrobromide is a thiamine metabolic inhibitor that can act as a substrate for thiamine pyrophosphokinase. Pyrithiamine hydrobromide can be used in the research of nervous system diseases .

For research use only. We do not sell to patients.

Pyrithiamine hydrobromide Chemical Structure

CAS No. : 534-64-5

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

420.14

Formula

C₁₄H₂₀Br₂N₄O

CAS No.

534-64-5

Appearance

Solid

Color

White to light yellow

SMILES

CC1=[N+](C=CC=C1CCO)CC2=C(N=C(N=C2)C)N.[Br-].Br

Initial Source

Microorganisms

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (238.02 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3802 mL	11.9008 mL	23.8016 mL
5 mM	0.4760 mL	2.3802 mL	4.7603 mL
10 mM	0.2380 mL	1.1901 mL	2.3802 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 96.61%

Select Batch:

Data Sheet (266 KB) SDS (393 KB)

COA (245 KB) Elemental Analysis Report (103 KB)

Handling Instructions (2659 KB)

References

[1]. Liu JY, et al. Pyrithiamine as a substrate for thiamine pyrophosphokinase. J Biol Chem. 2006 Mar 10;281(10):6601-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.3802 mL	11.9008 mL	23.8016 mL	59.5040 mL
	5 mM	0.4760 mL	2.3802 mL	4.7603 mL	11.9008 mL
	10 mM	0.2380 mL	1.1901 mL	2.3802 mL	5.9504 mL
	15 mM	0.1587 mL	0.7934 mL	1.5868 mL	3.9669 mL
	20 mM	0.1190 mL	0.5950 mL	1.1901 mL	2.9752 mL
	25 mM	0.0952 mL	0.4760 mL	0.9521 mL	2.3802 mL
	30 mM	0.0793 mL	0.3967 mL	0.7934 mL	1.9835 mL
	40 mM	0.0595 mL	0.2975 mL	0.5950 mL	1.4876 mL
	50 mM	0.0476 mL	0.2380 mL	0.4760 mL	1.1901 mL
	60 mM	0.0397 mL	0.1983 mL	0.3967 mL	0.9917 mL
	80 mM	0.0298 mL	0.1488 mL	0.2975 mL	0.7438 mL
	100 mM	0.0238 mL	0.1190 mL	0.2380 mL	0.5950 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.