Pyrithiamine hydrobromide

Cat. No.: HY-122273: FAQs
Data Sheet SDS COA Handling Instructions

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Pyrithiamine hydrobromide is a thiamine metabolic inhibitor that can act as a substrate for thiamine pyrophosphokinase. Pyrithiamine hydrobromide can be used in the research of nervous system diseases .

For research use only. We do not sell to patients.

Pyrithiamine hydrobromide Chemical Structure

CAS No. : 534-64-5

Size	Price	Stock
1 mg	USD 200	Ask For Quote & Lead Time
5 mg	USD 500	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Purity & Documentation
References
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Description

Molecular Weight

420.14

Formula

C₁₄H₂₀Br₂N₄O

CAS No.

534-64-5

Appearance

Solid

Color

White to light yellow

SMILES

CC1=[N+](C=CC=C1CCO)CC2=C(N=C(N=C2)C)N.[Br-].Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : ≥ 5 mg/mL (11.90 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3802 mL	11.9008 mL	23.8016 mL
5 mM	0.4760 mL	2.3802 mL	4.7603 mL
10 mM	0.2380 mL	1.1901 mL	2.3802 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥95.0%

Select Batch:

Data Sheet (266 KB) SDS (393 KB)

COA (245 KB) Elemental Analysis Report (103 KB)

Handling Instructions (2659 KB)

References

[1]. Liu JY, et al. Pyrithiamine as a substrate for thiamine pyrophosphokinase. J Biol Chem. 2006 Mar 10;281(10):6601-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.3802 mL	11.9008 mL	23.8016 mL	59.5040 mL
	5 mM	0.4760 mL	2.3802 mL	4.7603 mL	11.9008 mL
	10 mM	0.2380 mL	1.1901 mL	2.3802 mL	5.9504 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.