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Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers.

For research use only. We do not sell to patients.

Quazolast Chemical Structure

Quazolast Chemical Structure

CAS No. : 86048-40-0

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Quazolast Related Antibodies

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Description

Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers[1][2].

In Vivo

Quazolast (0.2, 1, 5 mg/kg; p.o.) reduces the gastric damage in rats induced by absolute ethanol (0.9 mg/kg)[1].
Quazolast (3.1, 6.3, 12.5, 25 mg/kg; p.o.) reduces the gastric damage associated with 0.6 N HC1 administration[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 150 g Male Sprague Dawley rat[1]
Dosage: 0.2, 1, 5 mg/kg
Administration: P.o.
Result: Decreased the rat gastric mucosa damage in a dose dependent manner and reduced the gastric ulcer index (68%) at 5 mg/kg in rat induced by absolute ethanol (0.9 mg/kg).
Molecular Weight

262.65

Formula

C12H7ClN2O3
CAS No.
SMILES

COC(C1=NC2=CC(Cl)=C3C(N=CC=C3)=C2O1)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Quazolast Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Quazolast86048-40-0RHC 3988RHC3988RHC-3988Othersgastric ulcersorally activeHC1ethanolnasal itchinessInhibitorinhibitorinhibit

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