Quazolast  (Synonyms: RHC 3988)

Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers^[1][2].

Quazolast (0.2, 1, 5 mg/kg; p.o.) reduces the gastric damage in rats induced by absolute ethanol (0.9 mg/kg)^[1].
Quazolast (3.1, 6.3, 12.5, 25 mg/kg; p.o.) reduces the gastric damage associated with 0.6 N HC1 administration^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

262.65

C₁₂H₇ClN₂O₃

86048-40-0

COC(C1=NC2=CC(Cl)=C3C(N=CC=C3)=C2O1)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Fitzpatrick LR, et al. Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats. Agents Actions. 1991 Jul;33(3-4):330-6.  [Content Brief]

  [2]. Dave NK, et al. A controlled, double-blind study of the effect of quazolast on nasal challenge with ragweed antigen. Ann Allergy. 1990 Oct;65(4):298-302.  [Content Brief]