2. Metabolic Enzyme/Protease
  3. Amylases
  4. Quercetin 3-(6″-caffeoylsophoroside)

Quercetin 3-(6″-caffeoylsophoroside) is an orally active α-amylase inhibitor, with an IC50 of 73.66 μg/mL. Quercetin 3-(6″-caffeoylsophoroside) presents in thehydro-methanolic extract of Cardamine hirsuta Linn. Quercetin 3-(6″-caffeoylsophoroside) shows the antidiabetic activities by oxidative stress reduction and α-amylase inhibition. Quercetin 3-(6″-caffeoylsophoroside) can be used for diabetes mellitus research.

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Quercetin 3-(6″-caffeoylsophoroside) Chemical Structure

Quercetin 3-(6″-caffeoylsophoroside) Chemical Structure

CAS No. : 1032595-77-9

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Quercetin 3-(6″-caffeoylsophoroside) Related Antibodies

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Description

Quercetin 3-(6″-caffeoylsophoroside) is an orally active α-amylase inhibitor, with an IC50 of 73.66 μg/mL. Quercetin 3-(6″-caffeoylsophoroside) presents in thehydro-methanolic extract of Cardamine hirsuta Linn. Quercetin 3-(6″-caffeoylsophoroside) shows the antidiabetic activities by oxidative stress reduction and α-amylase inhibition. Quercetin 3-(6″-caffeoylsophoroside) can be used for diabetes mellitus research[1].

In Vivo

Quercetin 3-(6″-caffeoylsophoroside) (50, 100, 500, 1000, and 2000 mg/kg, p.o.) shows safety in acute oral toxicity of SD rats and can be used in anti-diabetic research[1].
Quercetin 3-(6″-caffeoylsophoroside) (125, 250, 500 mg/kg, p.o.) improves type 2 diabetes mellitus of SD rats by oxidative stress reduction and α-amylase inhibition[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: FED HFD (45% fat) for 30 days to induce type 2 diabetes mellitus in SD rats[1]
Dosage: 125, 250, 500 mg/kg
Administration: Oral gavage (p.o.)
Result: Significantly decreased the blood glucose level, improved biochemical parameters as well as oxidative stress by reduction of lipid peroxidation, and increased high-density lipoproteins with dose of 500mg/kg.
Enhanced activities of glutathione-s-transferase, glutathione, superoxide dismutase.
Restored cellular architecture in the histopathological examination.
Animal Model: Acute oral toxicity in 8-week male SD rats[1]
Dosage: 50, 100, 500, 1000, and 2000 mg/kg
Administration: Oral gavage (p.o.)
Result: Safe for use in anti-diabetic research.
Molecular Weight

532.63

Formula

C27H40N4O7
CAS No.
SMILES

O=C(CCC(N(C(C1=C(OC)C(OC)=CC=C1)C(NC(C)(C)C)=O)CCCOCC)=O)NC2=NOC(C)=C2
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Quercetin 3-(6″-caffeoylsophoroside) Related Classifications

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Keywords:

Quercetin 3-(6″-caffeoylsophoroside)1032595-77-9AmylasesAntidiabetic AgentDiabetes mellitus (T2DM)α-amylase inhibitoroxidative stressInhibitorinhibitorinhibit

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