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Quinacrine mustard dihydrochloride 

Cat. No.: HY-W127705 Purity: 95.01%
COA Handling Instructions

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Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes.

For research use only. We do not sell to patients.

Quinacrine mustard dihydrochloride Chemical Structure

Quinacrine mustard dihydrochloride Chemical Structure

CAS No. : 4213-45-0

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5 mg USD 86 In-stock
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Based on 1 publication(s) in Google Scholar

Quinacrine mustard dihydrochloride Related Antibodies

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Description

Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes[1][2][3].

In Vitro

Quinacrine mustard dihydrochloride (5 μg/ml) can be used for the DNA strain of plant, animal, or human chromosomes[1].
Quinacrine mustard dihydrochloride (28 μM) increases the number of mutants that appeared after an exposure of bacteria[2].
quinacrine mustard dihydrochloride (0.2 μM; 4h) induces cell cycle arrest at G2+M-phase in HL-60 cells[3].
Caffeine (5 mM) prevents the cytotoxic action of quinacrine mustard dihydrochloride (0.2 μM; 4h) in HL-60 cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Quinacrine mustard dihydrochloride Related Antibodies

Cell Cycle Analysis[3]

Cell Line: HL-60 cells
Concentration: 0.2 µM
Incubation Time: 4 h
Result: Induced cell cycle arrest at G2+M-phase with the accumulation of cells in this compartment by 50%.
Molecular Weight

541.77

Formula

C23H30Cl5N3O
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC(CCCN(CCCl)CCCl)N=C1C2=C(C=C(C=C2)Cl)NC3=C1C=C(C=C3)OC.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 6.25 mg/mL (11.54 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8458 mL 9.2290 mL 18.4580 mL
5 mM 0.3692 mL 1.8458 mL 3.6916 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 95.01%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.8458 mL 9.2290 mL 18.4580 mL 46.1450 mL
5 mM 0.3692 mL 1.8458 mL 3.6916 mL 9.2290 mL
10 mM 0.1846 mL 0.9229 mL 1.8458 mL 4.6145 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Quinacrine mustard dihydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Quinacrine mustard4213-45-0Fluorescent Dyechromosomal DNAHL-60 cellsaromatic agentmutagenic agentG2/M-phaseInhibitorinhibitorinhibit

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