1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. iGluR
  3. (R)-3,4-DCPG

(R)-3,4-DCPG is an AMPA and NMDA antagonist with a Kd of 77 μM for AMPA. (R)-3,4-DCPG complete antagonizes the NMDA-induced depolarization at a concentration of 500 μM. (R)-3,4-DCPG exhibits a weak antagonistic effect on kainate-induced depolarizations.

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(R)-3,4-DCPG Chemical Structure

(R)-3,4-DCPG Chemical Structure

CAS No. : 201730-10-1

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Description

(R)-3,4-DCPG is an AMPA and NMDA antagonist with a Kd of 77 μM for AMPA. (R)-3,4-DCPG complete antagonizes the NMDA-induced depolarization at a concentration of 500 μM. (R)-3,4-DCPG exhibits a weak antagonistic effect on kainate-induced depolarizations[1].

Molecular Weight

239.18

Formula

C10H9NO6

CAS No.
SMILES

O=C(C1=CC=C([C@@H](N)C(O)=O)C=C1C(O)=O)O

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(R)-3,4-DCPG
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HY-107519
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