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  4. (R)-DZD1516

(R)-DZD1516 is the R enantiomer of DZD1516 (HY-155079). DZD1516 is a potent and selective HER2 inhibitor.

For research use only. We do not sell to patients.

(R)-DZD1516 Chemical Structure

(R)-DZD1516 Chemical Structure

CAS No. : 2387570-03-6

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1 mg USD 230 In-stock
5 mg USD 590 In-stock
10 mg USD 950 In-stock
25 mg USD 1900 In-stock
50 mg USD 3050 In-stock
100 mg USD 4900 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of (R)-DZD1516:

(R)-DZD1516 Related Antibodies

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Description

(R)-DZD1516 is the R enantiomer of DZD1516 (HY-155079). DZD1516 is a potent and selective HER2 inhibitor[1].

Molecular Weight

547.56

Formula

C28H27F2N7O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC1=CC2=C(C(NC3=CC=C(C(C)=C3)OC4=CC5=NC=NN5C=C4)=NC=N2)C(O[C@@H]6CCN(CC6(F)F)C)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (182.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8263 mL 9.1314 mL 18.2628 mL
5 mM 0.3653 mL 1.8263 mL 3.6526 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8263 mL 9.1314 mL 18.2628 mL 45.6571 mL
5 mM 0.3653 mL 1.8263 mL 3.6526 mL 9.1314 mL
10 mM 0.1826 mL 0.9131 mL 1.8263 mL 4.5657 mL
15 mM 0.1218 mL 0.6088 mL 1.2175 mL 3.0438 mL
20 mM 0.0913 mL 0.4566 mL 0.9131 mL 2.2829 mL
25 mM 0.0731 mL 0.3653 mL 0.7305 mL 1.8263 mL
30 mM 0.0609 mL 0.3044 mL 0.6088 mL 1.5219 mL
40 mM 0.0457 mL 0.2283 mL 0.4566 mL 1.1414 mL
50 mM 0.0365 mL 0.1826 mL 0.3653 mL 0.9131 mL
60 mM 0.0304 mL 0.1522 mL 0.3044 mL 0.7610 mL
80 mM 0.0228 mL 0.1141 mL 0.2283 mL 0.5707 mL
100 mM 0.0183 mL 0.0913 mL 0.1826 mL 0.4566 mL
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(R)-DZD1516 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-DZD15162387570-03-6OthersR enantiomerInhibitorinhibitorinhibit

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