2. Anti-infection
  3. Reverse Transcriptase
  4. (R)-Efavirenz

(R)-Efavirenz  (Synonyms: (R)-DMP 266; (R)-EFV; (R)-L-743726)

Cat. No.: HY-10572A
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(R)-Efavirenz ((R)-DMP 266) is a non-nucleoside reverse transcriptase inhibitor that acts by non-competitive inhibition of the viral enzyme. (R)-Efavirenz can be metabolized by CYP2B6 to 8-hydroxyefavirenz in a highly stereoselective manner. (R)-Efavirenz is promising to be a useful probe for the CYP2B6 active site and catalytic mechanisms.

For research use only. We do not sell to patients.

(R)-Efavirenz Chemical Structure

(R)-Efavirenz Chemical Structure

CAS No. : 154801-74-8

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(R)-Efavirenz Related Antibodies

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Description

(R)-Efavirenz ((R)-DMP 266) is a non-nucleoside reverse transcriptase inhibitor that acts by non-competitive inhibition of the viral enzyme. (R)-Efavirenz can be metabolized by CYP2B6 to 8-hydroxyefavirenz in a highly stereoselective manner. (R)-Efavirenz is promising to be a useful probe for the CYP2B6 active site and catalytic mechanisms[1][2].

Molecular Weight

315.67

Formula

C14H9ClF3NO2
CAS No.
SMILES

FC(F)(F)[C@]1(C2=CC(Cl)=CC=C2NC(O1)=O)C#CC3CC3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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(R)-Efavirenz Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-Efavirenz154801-74-8(R)-DMP 266 (R)-EFV (R)-L-743726Reverse Transcriptasenon-nucleoside reverse transcriptaseviral enzymeCYP2B68-hydroxyefavirenzstereoselectiveInhibitorinhibitorinhibit

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