1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. iGluR
  3. (R)-Lanicemine

(R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects.

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(R)-Lanicemine Chemical Structure

(R)-Lanicemine Chemical Structure

CAS No. : 190581-71-6

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Description

(R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1].

Molecular Weight

198.26

Formula

C13H14N2

CAS No.
SMILES

N[C@@H](C1=CC=CC=C1)CC2=CC=CC=N2

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(R)-Lanicemine
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HY-108235C
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