1. Apoptosis
  2. MDM-2/p53
  3. (R)-NVP-CGM097

(R)-NVP-CGM097 is the R-enantiomer of NVP-CGM097 (HY-15954). NVP-CGM097 is a potent and selective MDM2 inhibitor with an IC50 of 1.7 nM for hMDM2.

For research use only. We do not sell to patients.

(R)-NVP-CGM097 Chemical Structure

(R)-NVP-CGM097 Chemical Structure

CAS No. : 2643938-26-3

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Description

(R)-NVP-CGM097 is the R-enantiomer of NVP-CGM097 (HY-15954). NVP-CGM097 is a potent and selective MDM2 inhibitor with an IC50 of 1.7 nM for hMDM2[1].

Molecular Weight

659.26

Formula

C38H47ClN4O4

CAS No.
SMILES

O=C1N(C2=CC=C(C=C2)N(C)CC3CCC(N4CC(N(CC4)C)=O)CC3)[C@H](C5=CC=C(C=C5)Cl)C6=CC(OC(C)C)=C(OC)C=C6C1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(R)-NVP-CGM097
Cat. No.:
HY-15954C
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