1. Apoptosis
  2. Bcl-2 Family
  3. (Rac)-Lisaftoclax

(Rac)-Lisaftoclax  (Synonyms: (Rac)-APG-2575)

Cat. No.: HY-129179B Purity: 98.22%
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(Rac)-Lisaftoclax ((Rac)-APG-2575) is a Bcl-2 inhibitor that can be uesd for hematologic malignancy research (CN112898295A).

For research use only. We do not sell to patients.

(Rac)-Lisaftoclax Chemical Structure

(Rac)-Lisaftoclax Chemical Structure

CAS No. : 2651980-10-6

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Based on 1 publication(s) in Google Scholar

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Description

(Rac)-Lisaftoclax ((Rac)-APG-2575) is a Bcl-2 inhibitor that can be uesd for hematologic malignancy research (CN112898295A)[1].

Molecular Weight

882.42

Formula

C45H48ClN7O8S

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(NS(=O)(C1=CC=C(NCC2OCCOC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCN(CC(CC5)=C(C6=CC=C(Cl)C=C6)CC75CCC7)CC4)C=C3OC8=CN=C(NC=C9)C9=C8

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 0.5 mg/mL (0.57 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(Rac)-Lisaftoclax
Cat. No.:
HY-129179B
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