(±)-ErSO

Cat. No.: HY-132247A: FAQs
Data Sheet Handling Instructions

Molarity Calculator

(±)-ErSO is the racemate of ErSO. ErSO is a selective anticipatory unfolded protein response (a-UPR) activator.

For research use only. We do not sell to patients.

(±)-ErSO Chemical Structure

CAS No. : 2407860-40-4

Size	Price	Stock	Quantity
5 mg	USD 350	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	USD 580	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
25 mg	USD 1100	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	USD 1700	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 mg	USD 2500	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

Synthetic products have potential research and development risk.

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (±)-ErSO:

ErSO Get quote
(S)-ErSO Get quote

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

(±)-ErSO is the racemate of ErSO. ErSO is a selective anticipatory unfolded protein response (a-UPR) activator^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	0.093 μM Compound: 1	Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 168 hrs by alamar blue assay Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 168 hrs by alamar blue assay	[PMID: 35080871]
HCT-116	IC₅₀	0.26 μM Compound: 1	Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay	[PMID: 35080871]
HCT-116	IC₅₀	11 μM Compound: 1	Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay Anticancer activity against ERalpha negative human HCT-116 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay	[PMID: 35080871]
HT-29	IC₅₀	0.21 μM Compound: 1	Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay	[PMID: 35080871]
HT-29	IC₅₀	0.25 μM Compound: 1	Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay Anticancer activity against ERalpha negative human HT-29 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay	[PMID: 35080871]
MCF7	IC₅₀	0.014 μM Compound: 1	Anticancer activity against ERalpha positive human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay Anticancer activity against ERalpha positive human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay	[PMID: 35080871]
MCF7	IC₅₀	0.02 μM Compound: 1	Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay	[PMID: 35080871]
MDA-MB-231	IC₅₀	23 μM Compound: 1	Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay	[PMID: 35080871]
MDA-MB-231	IC₅₀	6 μM Compound: 1	Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 168 hrs by alamar blue assay Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 168 hrs by alamar blue assay	[PMID: 35080871]
MDA-MB-231	IC₅₀	8 μM Compound: 1	Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay Anticancer activity against ERalpha negative human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay	[PMID: 35080871]
MDA-MB-436	IC₅₀	14 μM Compound: 1	Anticancer activity against ERalpha negative human MDA-MB-436 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay Anticancer activity against ERalpha negative human MDA-MB-436 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue assay	[PMID: 35080871]
MDA-MB-436	IC₅₀	22 μM Compound: 1	Anticancer activity against ERalpha negative human MDA-MB-436 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay Anticancer activity against ERalpha negative human MDA-MB-436 cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay	[PMID: 35080871]
T47D	IC₅₀	0.01 μM Compound: 1	Anticancer activity against human T47D cells harbouring ERalphaY537S mutant assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay Anticancer activity against human T47D cells harbouring ERalphaY537S mutant assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay	[PMID: 35080871]
T47D	IC₅₀	0.015 μM Compound: 1	Anticancer activity against human T47D cells harbouring ERalphaD538G mutant assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay Anticancer activity against human T47D cells harbouring ERalphaD538G mutant assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay	[PMID: 35080871]
T47D	IC₅₀	0.02 μM Compound: 1	Anticancer activity against ERalpha positive human T47D cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay Anticancer activity against ERalpha positive human T47D cells assessed as cell growth inhibition incubated for 24 hrs by alamar blue assay	[PMID: 35080871]

Molecular Weight

453.33

Formula

C₂₂H₁₃F₆NO₃

CAS No.

2407860-40-4

Appearance

Solid

Color

Light yellow to orange

SMILES

O=C1NC2=C(C=CC=C2C(F)(F)F)C1(C3=CC=C(O)C=C3)C4=CC=C(OC(F)(F)F)C=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Boudreau MW, et al. A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice. Sci Transl Med. 2021;13(603):eabf1383. [Content Brief]

(±)-ErSO Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)-ErSO2407860-40-4OthersInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

(±)-ErSO

Customer Review

Other Forms of (±)-ErSO:

(±)-ErSO Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

(±)-ErSO Related Classifications

Molarity Calculator

Dilution Calculator

The molarity calculator equation

The dilution calculator equation

Keywords:

Your Recently Viewed Products:

Customer Review

Request for HNMR Report

SAFETY DATA SHEET (SDS)

Request for HNMR Report