1. Neuronal Signaling
  2. Sigma Receptor
  3. (±)-PPCC

(±)-PPCC is a sigma-1 agonist that mainly interacts with sigma-1 receptors with Ki of 1.5 nM. (±)-PPCC has effective anti-amnesia effects in rats with mild or severe cognitive impairment, and can improve the cognitive abilities of rats.

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(±)-PPCC Chemical Structure

(±)-PPCC Chemical Structure

CAS No. : 932736-90-8

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Description

(±)-PPCC is a sigma-1 agonist that mainly interacts with sigma-1 receptors with Ki of 1.5 nM. (±)-PPCC has effective anti-amnesia effects in rats with mild or severe cognitive impairment, and can improve the cognitive abilities of rats[1].

IC50 & Target

Ki: 1.5 nM (sigma-1)[1].

Molecular Weight

379.49

Formula

C24H29NO3

CAS No.
SMILES

COC([C@]1(C2=CC=C(C=C2)C)[C@@H](C1)CN3CCC(CC3)(C4=CC=CC=C4)O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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(±)-PPCC Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(±)-PPCC
Cat. No.:
HY-111081
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