2. Anti-infection
  3. HCV
  4. Radalbuvir

Radalbuvir (GS-9669) is a non-nucleoside inhibitor of nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp). Radalbuvir shows strong anti-HCV potency (GT1a intrinsic EC50 = 2.9 nM, GT1b EC50 = 6 nM).

For research use only. We do not sell to patients.

Radalbuvir Chemical Structure

Radalbuvir Chemical Structure

CAS No. : 1314795-11-3

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Radalbuvir Related Antibodies

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Description

Radalbuvir (GS-9669) is a non-nucleoside inhibitor of nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp). Radalbuvir shows strong anti-HCV potency (GT1a intrinsic EC50 = 2.9 nM, GT1b EC50 = 6 nM)[1].

In Vitro

Radalbuvir (GS-9669) shows high in vitro metabolic stability, long residence time in rats, and maintained high activity against the NS5B M423T mutation (GT1b M423T EC50 = 14 nM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Radalbuvir Related Antibodies
Clinical Trial
Molecular Weight

543.71

Formula

C30H41NO6S
CAS No.
SMILES

O=C([C@@H]1CCC(C)=CC1)N([C@H]2CC[C@@](CO[C@H]3CCOC3)(O)CC2)C(C=C(C#CC(C)(C)C)S4)=C4C(O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Radalbuvir Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Radalbuvir1314795-11-3GS-9669GS9669GS 9669HCVHepatitis C virusnon-nucleoside inhibitorNS5BRdRpnonstructural protein 5BRNA-dependent RNA polymeraseanti-HCVhigh in vitro metabolic stabilityInhibitorinhibitorinhibit

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HY-16750
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