ADAMTSL1/Punctin Protein, Human (sf9, His)

ADAMTSL1/Punctin Protein, a member of the ADAMTS family, encodes a unique secreted protein lacking metalloproteinase and disintegrin-like domains but retaining other ADAMTS domains, including the thrombospondin type 1 motif. Likely involved in crucial extracellular matrix functions, alternative splicing generates multiple transcript variants, each encoding distinct proteins. ADAMTSL1/Punctin Protein, Human (sf9, His) is the recombinant human-derived ADAMTSL1/Punctin protein, expressed by Sf9 insect cells , with C-His labeled tag.

ADAMTSL1, a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family, encodes a secreted protein. In contrast to typical ADAMTS family members, this protein lacks the metalloproteinase and disintegrin-like domains but retains other ADAMTS domains, including the thrombospondin type 1 motif. The protein is likely involved in crucial functions within the extracellular matrix. Alternative splicing generates multiple transcript variants, each encoding distinct proteins.

Human

Sf9 insect cells

C-His

Q8N6G6-2 (E29-H439)

92949  [NCBI]

Approximately 48 kDa.

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.