ADH7 Protein, Human (HEK293, His)

ADH7 Protein, Human (HEK293, His) is human recombinant ADH7 with His tag at the C-terminus. ADH7 Protein, Human (HEK293, His) is expressed by Mammalian expression system and the target gene encoding Met1-Phe386 is expressed.

ADH7 is a NADPH-dependent enzyme belongs to the superfamily of medium-chain alcohol dehydrogenase. ADH7 is regulated by miR-3065, and miR-3065 interacted with LINC01133. ADH7 is enriched in the retinoic acid metabolic process and the retinol metabolism pathway. ADH7 is significantly associated with the cervical cancer survival rate^[1][2].

Human

HEK293

C-6*His

P40394 (M1-F386)

131  [NCBI]

MFAEIQIQDKDRMGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTFHHHHHHHH

Approximately 44.0 kDa

Greater than 80% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.

• [1]. Ding S, et al. ADH7, miR-3065 and LINC01133 are associated with cervical cancer progression in different age groups. Oncol Lett. 2020 Mar;19(3):2326-2338.  [Content Brief]

  [2]. Nguyen TT, et al. The ADH7 Promoter of Saccharomyces cerevisiae is Vanillin-Inducible and Enables mRNA Translation Under Severe Vanillin Stress. Front Microbiol. 2015 Dec 11;6:1390.  [Content Brief]