ALDH7A1 Protein, Human (His)

ALDH7A1, a multifunctional enzyme, plays a crucial role in mediating protective effects. It metabolizes betaine aldehyde into betaine, acting as a significant cellular osmolyte and methyl donor. Furthermore, ALDH7A1 safeguards cells from oxidative stress by metabolizing various aldehydes derived from lipid peroxidation. Additionally, it participates in lysine catabolism. ALDH7A1 Protein, Human (His) is the recombinant human-derived ALDH7A1 protein, expressed by E. coli , with N-His labeled tag. The total length of ALDH7A1 Protein, Human (His) is 510 a.a., with molecular weight of ~56 KDa.

ALDH7A1, a versatile enzyme, plays a crucial role in mediating essential protective effects within cells. It catalyzes the conversion of betaine aldehyde to betaine, serving as a vital cellular osmolyte and methyl donor. Notably, ALDH7A1 functions as a protective shield against oxidative stress by metabolizing various aldehydes derived from lipid peroxidation. Furthermore, the enzyme actively participates in lysine catabolism, contributing to broader metabolic processes. Through its multifaceted activities, ALDH7A1 emerges as a key player in cellular defense mechanisms and essential metabolic pathways.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-His

P49419-2 (S2-Q511)

501  [NCBI]

STLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ

Approximately 57 kDa.

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 500 mM NaCl, 20% Glycerol, 5% Trehalose, 5% Mannitol, 0.01% Tween-80.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.