Alpha-2-Antiplasmin/Serpin F2 Protein, Rat (HEK293, His)

Alpha-2-antiplasmin/serpin F2 protein is an important member of the serine protease inhibitor family and plays a key role as a serine protease inhibitor, regulating proteolytic activity. His research enhances the understanding of cellular processes related to proteolysis and its therapeutic applications. Alpha-2-Antiplasmin/Serpin F2 Protein, Rat (HEK293, His) is the recombinant rat-derived Alpha-2-Antiplasmin/Serpin F2 protein, expressed by HEK293 , with C-His labeled tag.

The Alpha-2-Antiplasmin/Serpin F2 Protein is an integral member of the serpin family, highlighting its pivotal role as a serine protease inhibitor. As part of this family, Alpha-2-Antiplasmin/Serpin F2 likely shares conserved structural and functional features with related proteins, emphasizing its involvement in regulating proteolytic activities. The classification within the serpin family underscores its specific designation within the broader context of serine protease inhibitors, offering insights into its unique mechanisms and substrate specificity. The study of Alpha-2-Antiplasmin/Serpin F2 contributes to our understanding of its role in cellular processes related to proteolysis, providing potential applications in therapeutic interventions and a deeper comprehension of its broader impact on cellular processes involved in protein metabolism. Further exploration of Alpha-2-Antiplasmin/Serpin F2's role holds promise for enhancing our knowledge of its contributions to both normal physiology and pathological conditions.

Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (HY-P2185A) that incubate at 37 °C for 15 minutes. The IC₅₀ value is 0.1895 nM.

Rat

HEK293

C-10*His

Q68FT8 (M28-K491)

287527  [NCBI]

MDLPGQQPVSEQAQQKLPPLALLKLGNQDLGDHATLKRSPGDCKSAPTTEETRRLSQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGARNQTLENLQRVLHMNMGSCIPHLLSHFCQNLNPGTIRLAARIYLQKGFPIKDDFLEQSEKLFGAKPVKLTGRQEEDLMNINKWVKEATEGKIEDFLSELPDNTVLLLLNAIHFHGFWRTKFDPSLTQKDSFHLDEQFTVPVAMMHAQSYPLRWFLLEQPEIQVAHFPFQNNMSFVVIMPTYFGWNVSEVLANLTWDTLYQPSMREKPTKVRLPKLHLEQHLDLVATLSKLGLQDLFQSPDLRGISDQSLVVSSVQHQSTMELSEAGVEAAAATSTAMTRMSLSSFFLNRPFIFFIMEETIGIPLFVGSVRNPDPSAQPQPQEQQDSPDNRRLDQNDKADIPGGKTFAPDLKLVPRLEEDYPQFSSPK

Approximately 58-90 kDa.

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  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.