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Alpha-Fetoprotein Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P700652
Handling Instructions

Alpha-Fetoprotein binds copper, nickel, and fatty acids, displaying particular affinity for bilirubin, albeit less efficiently than serum albumin. Its structural variations, including dimeric and trimeric forms, alongside the monomeric state, contribute to the protein's versatile functionality. This complexity in molecular interactions with diverse ligands underscores Alpha-Fetoprotein's significance in various physiological processes. Alpha-Fetoprotein Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Alpha-Fetoprotein protein, expressed by HEK293 , with C-His labeled tag. The total length of Alpha-Fetoprotein Protein, Cynomolgus (HEK293, His) is 591 a.a., with molecular weight of 68-75 kDa.

For research use only. We do not sell to patients.

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Description

Alpha-Fetoprotein binds copper, nickel, and fatty acids, displaying particular affinity for bilirubin, albeit less efficiently than serum albumin. Its structural variations, including dimeric and trimeric forms, alongside the monomeric state, contribute to the protein's versatile functionality. This complexity in molecular interactions with diverse ligands underscores Alpha-Fetoprotein's significance in various physiological processes. Alpha-Fetoprotein Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Alpha-Fetoprotein protein, expressed by HEK293 , with C-His labeled tag. The total length of Alpha-Fetoprotein Protein, Cynomolgus (HEK293, His) is 591 a.a., with molecular weight of 68-75 kDa.

Background

The Alpha-Fetoprotein Protein exhibits diverse binding capabilities, including the ability to bind copper, nickel, and fatty acids. Notably, it demonstrates affinity for bilirubin, although less efficiently than serum albumin. The protein exists in various forms, with dimeric and trimeric structures identified in addition to the monomeric form. These structural variations likely contribute to the functional versatility of Alpha-Fetoprotein, suggesting a complex interplay in its molecular interactions with different ligands and emphasizing its significance in various physiological processes.

Species

Cynomolgus

Source

HEK293

Tag

C-His

Accession

A0A2K5U7U0 (R19-V609)

Gene ID

/

Molecular Construction
N-term
Alpha-Fetoprotein (R19-V609)
Accession # A0A2K5U7U0
His
C-term
Synonyms
rHuAlpha-Fetoprotein, His; AFP; Alpha-Fetoprotein
Molecular Weight

68-75 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Alpha-Fetoprotein Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Alpha-Fetoprotein Protein, Cynomolgus (HEK293, His)
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HY-P700652
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