Apolipoprotein M/APOM Protein, Mouse (P.pastoris, His)

Apolipoprotein M (APOM) is likely involved in lipid transport, binding various molecules, including sphingosine-1-phosphate, myristic acid, palmitic acid, stearic acid, retinol, all-trans-retinoic acid, and 9-cis-retinoic acid. Interacting with LRP2, APOM undergoes renal uptake facilitated by LRP2, followed by lysosomal degradation. This suggests APOM's role in mediating dynamic lipid and retinoid metabolism processes within the body. Apolipoprotein M/APOM Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Apolipoprotein M/APOM, expressed by P. pastoris , with N-His labeled tag.

Apolipoprotein M (APOM) is likely implicated in lipid transport, demonstrating the capacity to bind various molecules, including sphingosine-1-phosphate, myristic acid, palmitic acid, and stearic acid, as well as retinol, all-trans-retinoic acid, and 9-cis-retinoic acid. Through its interactions, APOM has been shown to engage with LRP2, whereby LRP2 facilitates the renal uptake of APOM, leading to subsequent lysosomal degradation. This suggests a role for APOM in mediating the dynamic processes of lipid and retinoid metabolism within the body.

Mouse

P. pastoris

N-His

Q9Z1R3 (M1-K190)

55938  [NCBI]

MFHQVWAALLSLYGLLFNSMNQCPEHSQLTALGMDDTETPEPHLGLWYFIAGAASTTEELATFDPVDNIVFNMAAGSAPRQLQLRATIRTKSGVCVPRKWTYRLTEGKGNMELRTEGRPDMKTDLFSSSCPGGIMLKETGQGYQRFLLYNRSPHPPEKCVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK

Approximately 30.0 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from 0.22 μm filtered solution in PBS, 3% Trehalose, pH 7.4.

<1.0 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.